2025 · Week 11
San Francisco 49ers at Arizona Cardinals
Nov 16, 2025 · University of Phoenix Stadium · closed · grass
Recap
San Francisco 49ers beat Arizona Cardinals 41–22. It was an upset by ScoutIndex's numbers — 49ers had just a 48% chance going in. 49ers improve to 7-4; Cardinals fall to 3-7. Christian McCaffrey led the way with 81 rushing yards and 2 rushing TDs; 5 catches for 40 yards and 1 TD. Cardinals out-gained the opponent 488–295 in total yards. Cardinals turned it over 3 times to 49ers's 0.
Team stats
| SF | ARI | |
|---|---|---|
| 21 | First downs | 23 |
| 295 | Total yards | 488 |
| 200 | Passing yards | 452 |
| 95 | Rushing yards | 36 |
| 19/26 | Comp / Att | 47/57 |
| 0 | Turnovers | 3 |
| 1 | Sacks taken | 0 |
Scoring & key plays
- Q1(14:47) 23-C.McCaffrey right guard for 1 yard, TOUCHDOWN.
- Q118-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- Q1(9:57) (Shotgun) 13-B.Purdy pass deep right to 85-G.Kittle for 30 yards, TOUCHDOWN [97-W.Nolen].
- Q118-E.Pineiro extra point is Blocked (36-K.Crawford), Center-46-J.Weeks, Holder-7-T.Morstead.
- Q1(5:03) 78-J.Fryar reported in as eligible. 20-Z.Knight left tackle for 6 yards, TOUCHDOWN.
- Q138-C.Ryland extra point is GOOD, Center-46-A.Brewer, Holder-39-P.O'Donnell.
- Q1(1:00) 38-C.Ryland 58 yard field goal is No Good, Wide Left, Center-46-A.Brewer, Holder-39-P.O'Donnell.
- Q2(13:44) 13-B.Purdy pass short left to 23-C.McCaffrey for 9 yards, TOUCHDOWN.
- Q218-E.Pineiro extra point is No Good, Wide Right, Center-46-J.Weeks, Holder-7-T.Morstead.
- Q2(6:34) 38-C.Ryland 26 yard field goal is GOOD, Center-46-A.Brewer, Holder-39-P.O'Donnell.
- Q2(1:06) 18-E.Pineiro 48 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- Q2(:00) 18-E.Pineiro 47 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- Q3(12:56) 78-J.Fryar reported in as eligible. 20-Z.Knight right tackle for 60 yards, TOUCHDOWN NULLIFIED by Penalty. PENALTY on ARI-49-P.Brown, Offensive Holding, 9 yards, enforced at ARI 40 - No Play.
- Q3(7:32) 18-E.Pineiro 47 yard field goal is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- Q3(2:37) (Shotgun) 13-B.Purdy pass short left to 85-G.Kittle for 4 yards, TOUCHDOWN.
- Q318-E.Pineiro extra point is GOOD, Center-46-J.Weeks, Holder-7-T.Morstead.
- Q4(8:32) (No Huddle, Shotgun) 7-J.Brissett pass short middle to 85-T.McBride for 10 yards, TOUCHDOWN.
- Q4(4:49) 23-C.McCaffrey right end for 4 yards, TOUCHDOWN.
- Q4(2:48) (No Huddle, Shotgun) 7-J.Brissett pass deep left to 4-G.Dortch for 17 yards, TOUCHDOWN.
Box score
SF
Passing
| Player | C/A | Yds | TD | INT |
|---|---|---|---|---|
| Brock Purdy | 19/26 | 200 | 3 | 0 |
Rushing
| Player | Car | Yds | TD |
|---|---|---|---|
| Brock Purdy | 1 | -7 | 0 |
| Christian McCaffrey | 13 | 81 | 2 |
| Brian Robinson | 8 | 24 | 0 |
| Mac Jones | 3 | -3 | 0 |
Receiving
| Player | Rec | Tgt | Yds | TD |
|---|---|---|---|---|
| Christian McCaffrey | 5 | 6 | 40 | 1 |
| George Kittle | 6 | 6 | 67 | 2 |
| Jauan Jennings | 4 | 6 | 54 | 0 |
| Kyle Juszczyk | 2 | 2 | 26 | 0 |
| Brian Robinson | 0 | 1 | 0 | 0 |
| Demarcus Robinson | 1 | 2 | 13 | 0 |
| Ricky Pearsall | 1 | 2 | 0 | 0 |
ARI
Passing
| Player | C/A | Yds | TD | INT |
|---|---|---|---|---|
| Jacoby Brissett | 47/57 | 452 | 2 | 2 |
Rushing
| Player | Car | Yds | TD |
|---|---|---|---|
| Jacoby Brissett | 2 | -2 | 0 |
| Bam Knight | 5 | 24 | 1 |
| Michael Carter | 2 | 6 | 0 |
| Emari Demercado | 5 | 8 | 0 |
Receiving
| Player | Rec | Tgt | Yds | TD |
|---|---|---|---|---|
| Michael Wilson | 15 | 18 | 185 | 0 |
| Trey McBride | 10 | 11 | 115 | 1 |
| Greg Dortch | 6 | 6 | 66 | 1 |
| Bam Knight | 4 | 4 | 21 | 0 |
| Michael Carter | 5 | 7 | 22 | 0 |
| Xavier Weaver | 2 | 3 | 15 | 0 |
| Emari Demercado | 2 | 3 | 12 | 0 |
| Elijah Higgins | 2 | 3 | 11 | 0 |
| Andre Baccellia | 1 | 1 | 5 | 0 |